Modulation of antigen presenting cell functions during chronic HPV infection
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some individuals they evade host immune responses and persist.Persistent HR-HPV infection of the cervix causes precancerous neoplasia that can eventuate in cervical cancer.Dendritic cells (DCs) are efficient in priming/cross-priming antigen-specific T cells and generatin